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Home/Hedge Funds/RTW Investments/Q3 2020

RTW Investments

Period: Q3 2020 Β· Filed: 2020-11-16
View on SEC EDGAR β†—
AUM
$4.15B
Total portfolio value
Positions
90
Reported securities
Top Holding
RCKT
9.3% $384.3M
QoQ Changes
+8 / -8
new Β· exited
⚠️13F Filing Disclosure

AUM figures shown are calculated by summing the reported market value of all positions in SEC 13F-HR filings β€” not the fund's actual assets under management.

  • Excludes cash, bonds, private equity, short positions, and foreign-listed stocks not required to be reported.
  • For PUT and CALL options, the reported Value is the notional value of the underlying shares β€” not the option premium paid. This significantly overstates the actual capital at risk.
  • Actual fund AUM is typically higher and includes strategies, instruments, and positions that never appear in a 13F.
  • 13F filings cover institutional managers with β‰₯$100M in 13F securities. Positions reflect end-of-quarter holdings, disclosed up to 45 days after the period ends.

Data sourced from SEC EDGAR. This tracker is for informational purposes only and does not constitute investment advice.

Portfolio Holdings

Top 30 positions

⚠️ Performance % calculated from filing date ( 2020-11-16) shown is the underlying stock price movement β€” not the derivative's P&L.
TickerIssuerNotionalPort %@ FilingNow (EOD)Since FilingAllocation
RCKTRocket Pharmaceuticals Inc$384.3M9.25%$22.86$3.84-83.2%
9.3%
IMVTImmunovant Inc$264.3M6.36%$35.19$38.79+10.2%
6.4%
ALNYAlnylam Pharmaceuticals Inc$244.8M5.90%$145.60$312.78+114.8%
5.9%
PTCTPTC Therapeutics Inc$186.7M4.49%$46.75$83.31+78.2%
4.5%
MRTXMirati Therapeutics Inc$182.0M4.38%β€”β€”
4.4%
DRNADicerna Pharmaceuticals Inc$130.0M3.13%β€”β€”
3.1%
MYOKMyokardia Inc$127.7M3.08%β€”β€”
3.1%
NTRANatera Inc$123.6M2.98%$72.24$279.32+286.7%
3.0%
AXSMAxsome Therapeutics Inc$119.0M2.87%$71.25$244.31+242.9%
2.9%
STOKStoke Therapeutics Inc$118.7M2.86%$33.49$32.70-2.4%
2.9%
RNAMAvidity Biosciences Inc$109.9M2.65%β€”β€”
2.6%
MASIMasimo Corp$106.3M2.56%$236.06β€”
2.6%
CERNCerner Corp$100.6M2.42%β€”β€”
2.4%
AXNXAxonics Modulation Technologies Inc$96.2M2.32%β€”β€”
2.3%
BAXBaxter International Inc$86.6M2.09%$71.97$22.65-68.5%
2.1%
TXG10x Genomics Inc$82.4M1.98%$124.68$39.01-68.7%
2.0%
ADVMAdverum Biotechnologies Inc$74.5M1.79%β€”β€”
1.8%
VCELVericel Corp$71.4M1.72%$18.53$46.98+153.5%
1.7%
TNDMTandem Diabetes Care Inc$68.5M1.65%$113.50$15.32-86.5%
1.6%
PTGXProtagonist Therapeutics Inc$66.6M1.60%$19.55$131.62+573.3%
1.6%
RLMDRelmada Therapeutics Inc$56.9M1.37%$37.62$6.28-83.3%
1.4%
ILMNIllumina Inc$54.1M1.30%$300.66$188.68-37.2%
1.3%
GHGuardant Health Inc$52.5M1.26%$111.78$167.98+50.3%
1.3%
AGENAgenus Inc$51.5M1.24%$78.51$3.49-95.5%
1.2%
TBIOTranslate Bio Inc$51.0M1.23%β€”$0.05
1.2%
FREQFrequency Therapeutics Inc$47.3M1.14%β€”β€”
1.1%
CLDXCelldex Therapeutics Inc$46.3M1.11%$14.83$38.37+158.7%
1.1%
ATHAAthira Pharma Inc$45.4M1.09%β€”β€”
1.1%
ESTAEstablishment Labs Holdings Inc$43.0M1.03%$18.53$89.25+381.6%
1.0%
NSTGQNanoString Technologies Inc$42.3M1.02%β€”β€”
1.0%

Quarter-on-Quarter Activity

Q3 2020 vs. Q2 2020

New Positions (8)

TickerIssuerNotionalSince Filing
ILMNIllumina Inc$54.1M-37.2%
GHGuardant Health Inc$52.5M+50.3%
ATHAAthira Pharma Inc$45.4M
CYTKCytokinetics Inc Private$40.7M
Trillium Therapeutics Inc$30.7M
INCYIncyte Corp$30.0M
VXRTVaxart Inc$23.4M
CELLBerkeley Lights Inc$22.9M

Exited Positions (8)

TickerIssuerNotional
WVEWAVE Life Sciences Ltd$24.9M
STAASTAAR Surgical Co$19.0M
NEONeogenomics Inc$13.8M
RPTXRepare Therapeutics Inc$7.0M
ARVNArvinas Inc$5.8M
NARIInari Med Inc$2.2M
FLGTFulgent Genetics Inc$1.2M
MOTSXXXXMotus Gi Hldgs Inc$1.0M

Increased (8)

TickerIssuerNotionalShares Ξ”Since Filing
ODTCOdonate Therapeutics Inc$-7.0M+107.7%
AMRSQAmyris Inc$2.7M+66.3%
PROFProfound Medical Corp$1.4M+40.2%
OSUROraSure Technologies Inc$7.3M+34.7%
IMVTImmunovant Inc$125.1M+31.4%+10.2%
CLDXCelldex Therapeutics Inc$12.3M+19.5%+158.7%
JNJJohnson & Johnson$4.5M+18.1%
CERNCerner Corp$19.6M+17.7%

Trimmed (6)

TickerIssuerNotionalShares Ξ”
FIXXHomology Medicines Inc$-39.2M-42.1%
BLUBellus Health Inc$-52.0M-29.7%
GNMKGenMark Diagnostics Inc$-2.9M-18.4%
ABUSArbutus Biopharma Corp$6.2M-13.0%
CSTLCastle Biosciences Inc$8.0M-7.5%
XGNExagen Inc$-2.0M-0.4%
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